Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 6, Number 2, February 2015, pages 51-54


Aortic Insufficiency Secondary to Enterococcus faecalis Endocarditis in an HIV-Positive Patient

Figure

Figure 1.
Figure 1. The valve shows inflammatory cells mixed with bacterial colonies (black areas on hematoxylin-eosin stain).

Tables

Table 1. Duke’s Criteria
 
If these criteria thresholds are not met or either an alternative explanation for illness is identified or the patient has defervesce within 4 days, endocarditis is highly unlikely.
Major criteria
 Two positive blood cultures for a typical microorganism of infective endocarditis
 Positive echocardiography (vegetation, myocardial abscess or new partial dehiscence of a prosthetic valve)
 New regurgitant murmur
Minor criteria
 Presence of a predisposing condition (fever >38 °C)
 Embolic disease
 Immunological phenomena
  Osler nodes
  Roth spots
  Glomerulonephritis
  Rheumatoid factor
 Positive blood cultures not meeting the major criteria or serologic evidence of active infection with an organism that causes endocarditis
 
A definite diagnosis of endocarditis (80% accuracy) is made with:
 2 major criteria
 1 major criterion and 3 minor criteria
 5 minor criteria
Possible endocarditis:
 1 major and 1 minor criterion
 3 minor criteria

 

Table 2. Enterococcal Endocarditis Medical Treatment
 
The recommended duration of combined therapy should be 4 - 6 weeks.
Penicillin+Streptomycin or gentamycin (aminoglycoside of choice due to less resistance)
 
Ampicillin 2 g IV every 4 h+Gentamycin 1 mg/kg IV every 8 h
Penicillin-G 3 - 4 × 106 units every 4 h+Gentamycin 1 mg/kg IV every 8 h
If patient is allergic to penicillin: vancomycin 15 mg/kg IV every 12 h+Gentamycin 1 mg/kg IV every 8 h