Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
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Case Report
Volume 6, Number 2, February 2015, pages 51-54
Aortic Insufficiency Secondary to Enterococcus faecalis Endocarditis in an HIV-Positive Patient
Figure
Tables
If these criteria thresholds are not met or either an alternative explanation for illness is identified or the patient has defervesce within 4 days, endocarditis is highly unlikely. |
Major criteria |
Two positive blood cultures for a typical microorganism of infective endocarditis |
Positive echocardiography (vegetation, myocardial abscess or new partial dehiscence of a prosthetic valve) |
New regurgitant murmur |
Minor criteria |
Presence of a predisposing condition (fever >38 °C) |
Embolic disease |
Immunological phenomena |
Osler nodes |
Roth spots |
Glomerulonephritis |
Rheumatoid factor |
Positive blood cultures not meeting the major criteria or serologic evidence of active infection with an organism that causes endocarditis |
A definite diagnosis of endocarditis (80% accuracy) is made with: |
2 major criteria |
1 major criterion and 3 minor criteria |
5 minor criteria |
Possible endocarditis: |
1 major and 1 minor criterion |
3 minor criteria |
The recommended duration of combined therapy should be 4 - 6 weeks. | ||
Penicillin | + | Streptomycin or gentamycin (aminoglycoside of choice due to less resistance) |
Ampicillin 2 g IV every 4 h | + | Gentamycin 1 mg/kg IV every 8 h |
Penicillin-G 3 - 4 × 106 units every 4 h | + | Gentamycin 1 mg/kg IV every 8 h |
If patient is allergic to penicillin: vancomycin 15 mg/kg IV every 12 h | + | Gentamycin 1 mg/kg IV every 8 h |