Figure 1. (A) Hematoxylin and eosin. Stratified squamous keratinized epithelium of the vulva is visualized with infiltrating tumor cells growing in nests, cords, and trabeculae. (B). Hematoxylin and eosin. Tumor cells are oval to polygonal-shaped with abundant coarsely granular eosinophilic cytoplasm. (C) S100 immunostaining with red chromogen. (D) Neuron-specific enolase immunostain.