| Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
| Journal website http://www.journalmc.org |
Case Report
Volume 4, Number 7, July 2013, pages 511-514
A Case of Community-Onset Bacterial Meningitis due to Extended-Spectrum Beta-Lactamase Producing Escherichia coli
Tables
| Drug | MIC (µg/mL) | Susceptibility |
|---|---|---|
| MIC: minimum inhibitory concentration. | ||
| Ampicillin | > 16 | R |
| Piperacillin | > 64 | R |
| Amoxicillin-clavulanate | 16 | I |
| Cefazolin | >16 | R |
| Cefotium | > 16 | R |
| Cefotaxime | > 32 | R |
| Ceftazidime | > 16 | R |
| Cefpirome | > 16 | R |
| Cefmetazole | ≤ 4 | S |
| Cefaclor | > 16 | R |
| Cefcapene-pivoxil | > 1 | R |
| Flomoxef | ≤ 8 | S |
| Cefoperazone-sulbactam | >16 | R |
| Imipenem-cilastatine | ≤ 1 | S |
| Aztreonam | > 16 | R |
| Gentamicin | > 8 | R |
| Amikacin | ≤ 4 | S |
| Levofloxacin | > 4 | R |
| Trimethoprim-sulfamethoxazole | ≤ 2 | S |
| Ref | Age | Gender | Background | Complication | Pathogen | Empiric therapy | Definitive therapy | Outcome |
|---|---|---|---|---|---|---|---|---|
| Ref: reference; Un: unknown; CTRX: ceftriaxone; Vanco: vancomycin; MEPM: meropenem; GM: gentamicin; CPFX: ciprofloxacin. | ||||||||
| 6 | 72 | F | Diabetes mellitus | Vertebral osteomyelitis | E. coli | CTRX + Vanco | MEPM + GM | Cured |
| 7 | 59 | Un | Nothing | Mycotic aneurysm | E. coli | CTX + ABPC + GM | MEPM + CPFX | Died |
| our case | 63 | M | Chronic renal failure, post-endoscopic sphincterotomy | Acute pyogenic cholangitis | E. coli | CTRX + Vanco | MEPM | Died |