Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
Journal website http://www.journalmc.org

Case Report

Volume 2, Number 2, April 2011, pages 76-80

Effective Switch From Twice-Daily Pre-Mixed Insulin 50/50 to Liraglutide to Achieve a Good Glycemic Control in Type 2 Diabetes

Figures

Figure 1.
Figure 1. (a) Blood glucose levels during insulin use. (b) Blood glucose levels during liraglutide use. B, L and D mean before breakfast, before lunch, and before dinner, respectively. Day means the day after the admission.
Figure 2.
Figure 2. Plasma glucose levels (a), % changes of plasma glucose levels from before breakfast (b), serum C-peptide levels (c), % changes of serum C-peptide levels from before breakfast (d). Open and closed boxes indicate values before and after the liraglutide use, respectively. BB, AB, BL, AL, BD, and AD mean before breakfast, two hours after breakfast, before lunch, two hours after lunch, before dinner, two hours after dinner, respectively.
Figure 3.
Figure 3. Changes in plasma glucose levels (a), % changes of plasma glucose levels from values before a glucagon-loading test (b), serum C-peptide levels (c), % changes of serum C-peptide levels from values before a glucagon-loading test (d). Open and closed boxes indicate values before and after the liraglutide use, respectively.
Figure 4.
Figure 4. Daily urinary C-peptide levels during insulin use (Open box) and liraglutide use (Closed box). Day means the day after the admission.
Figure 5.
Figure 5. Possible mechanisms for the liraglutide-mediated improvements in glycemic control suggested by our study.