Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 5, Number 8, August 2014, pages 452-454


Case Reports of Three Hypothyroid Patients Requiring Very High Doses of Levothyroxine

Table

Table 1. Demographic Profiles, Diagnoses and Treatments in the Three Cases
 
CaseGenderAgeBMIType of hypothyroidismCo-morbiditiesDosage of levothyroxineCause(s) of increased levothyroxine requirement
BMI: body mass index; HIV: human immunodeficiency virus; DI: diabetes insipidus; AVN: avascular necrosis.
1Female38 years30.9 kg/m2CentralHIV positive
Hypoadrenalism
DI
Hypertension
AVN both femoral heads
450 µg dailyEfavirenz 600 mg daily
2Female42 years51.1 kg/m2PrimaryMorbid obesity
PUD
Hypertension
Bronchial asthma
300 µg dailyMorbid obesity and cimetidine 400 mg twice daily
3Male18 years27.2 kg/m2PrimaryEpilepsy
Mental retardation
400 µg dailySodium valproate 400 mg twice daily