Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
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Case Report
Volume 5, Number 8, August 2014, pages 452-454
Case Reports of Three Hypothyroid Patients Requiring Very High Doses of Levothyroxine
Table
Case | Gender | Age | BMI | Type of hypothyroidism | Co-morbidities | Dosage of levothyroxine | Cause(s) of increased levothyroxine requirement |
---|---|---|---|---|---|---|---|
BMI: body mass index; HIV: human immunodeficiency virus; DI: diabetes insipidus; AVN: avascular necrosis. | |||||||
1 | Female | 38 years | 30.9 kg/m2 | Central | HIV positive Hypoadrenalism DI Hypertension AVN both femoral heads | 450 µg daily | Efavirenz 600 mg daily |
2 | Female | 42 years | 51.1 kg/m2 | Primary | Morbid obesity PUD Hypertension Bronchial asthma | 300 µg daily | Morbid obesity and cimetidine 400 mg twice daily |
3 | Male | 18 years | 27.2 kg/m2 | Primary | Epilepsy Mental retardation | 400 µg daily | Sodium valproate 400 mg twice daily |