| Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
| Journal website http://www.journalmc.org |
Case Report
Volume 8, Number 1, January 2017, pages 20-23
First Report of Treatment of Chronic Lymphocytic Leukemia in a Patient With Cystic Fibrosis
Table
| Cycle | Therapy | Complications |
|---|---|---|
| Treatment course 1: August 2013 - January 2014 | ||
| 1 | Bendamustine 100 mg/m2 (25% dose) × 2 days IVIG 400 mg/kg prophylaxis Acyclovir prophylaxis Septra DS tab M/W/F prophylaxis | Renal dysfunction from acyclovir therefore discontinued |
| 2 | Bendamustine (50% dose) × 2 days IVIG 400 mg/kg Septra DS tab M/W/F | |
| 3 | Bendamustine (70% dose) × 2 days IVIG 400 mg/kg Septra DS tab M/W/F | |
| 4 | Bendamustine (70% dose) × 2 days IVIG 400 mg/kg Septra DS tab M/W/F | |
| 5 | Bendamustine (100% dose) × 2 days IVIG 400 mg/kg Septra DS tab M/W/F prophylaxis | |
| 6 | Bendamustine (100% dose) × 2 days IVIG 400 mg/kg Septra DS tab M/W/F | |
| Treatment course 2: February 2015 - present | ||
| - | Ibrutinib 420 mg daily IVIG 400 mg/kg monthly | March 2015: Ascending cholangitis, Enterococcus bacteremia requiring hospital admission and IV piperacillin-tazobactam. Biliary stricture NYD requiring stenting. April 2015: respiratory symptoms responding to a 2-week course of doxycycline |