Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 8, Number 4, April 2017, pages 137-140

A Rare Case of Corynebacterium propinquum Endocarditis in a Native Valve

Figures

Figure 1.
Figure 1. Trans-esophageal echocardiogram revealed echodensities on the aortic (1) and mitral (2) valves.
Figure 2.
Figure 2. Etest with zones of clearance around penicillin, ceftriaxone, and vancomycin.

Table

Table 1. Sensitivity Patterns of All Reported Cases of Corynebacterium propinquum Native Valve Endocarditis
 
AntibioticsInterpretation (MIC in µg/mL) (if available)
Case 1 (infective endocarditis in an adult male with native valves)Case 2 (empyema in an adult male with squamous cell carcinoma)Case 3 (disseminated infection in an adult male with pulmonary TB)Case 4 (infective endocarditis in a girl child with ventricular septum defect)Case 5 (our patient)
PenicillinSensitive (< 0.03)Resistant (1.5)0.12< 0.016
Ampicillin0.25
AmoxicillinSensitive
OxacillinResistant
CephalothinSensitive
CefuroximeSensitiveResistant (8)
CefazolinSensitive0.12
CefamandoleSensitive
Cefotaxime0.12
CeftriaxoneSensitive (0.47)0.120.032
Cefepime0.25
VancomycinSensitiveResistant (64)Sensitive10.38
RifampicinSensitiveResistant (3)< 1
Linezolid< 2
GentamicinSensitiveResistant (6)Sensitive0.5
AmikacinSensitive
ErythromycinSensitiveResistant (6)
ClindamycinResistant (12)> 4
CiprofloxacinSensitive (0.006)Sensitive
NorfloxacinResistant
Levofloxacin1
ImipenemSensitive (0.015)
Meropenem< 0.03
TetracyclineSensitive (0.75)Sensitive
Sulfamethoxazole-trimethoprimSensitive (resistant to trimethoprim)Sensitive (2 - 38)> 2