Figure 1. Magnetic resonance imaging of the brain with increased T2-weighted density (black arrows) demonstrating toxic leukoencephalopathy involving the cerebral hemispheres.
| Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
| Journal website http://www.journalmc.org |
Case Report
Volume 8, Number 6, June 2017, pages 174-179
Toxic Leukoencephalopathy in a Teenager Caused by the Recreational Ingestion of 25I-NBOMe: A Case Report and Review of Literature
Figure
Tables
| 1. Agitation and akathisia |
| 2. Repetitive head rotating with neck in moderate extension |
| 3. Hyperreflexia and hypertonicity (greater in lower extremity) |
| 4. Clonus (greater in lower extremity) |
| 5. Myoclonus |
| 6. Tremor (greater in lower extremity) |
| 7. Hyperthermia |
| 8. Shivering |
| 9. Tachycardia |
| 10. Mydriasis |
| 11. Diaphoresis |
| 12. Increased bowel sounds and diarrhea |
| Ingestion of a known serotonergic agent and: |
| 1. Spontaneous clonus |
| 2. Inducible clonus or ocular clonus and agitation of diaphoresis |
| 3. Inducible clonus or ocular clonus and hypertonicity and temperature ≥ 38 °C |
| 4. Tremor and hyperreflexia |
| Ingestion of a known serotonergic agent and: |
| 1. Absence of other etiologies |
| 2. No recent addition or increase of a neuroleptic agent |
| 3. The presence of three of the following signs and symptoms: |
| a. Mental status changes |
| b. Agitation |
| c. Myoclonus |
| d. Hyperreflexia |
| e. Diaphoresis |
| f. Shivering |
| g. Tremor |
| h. Diarrhea |
| i. Incoordination |
| j. Fever |