| Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc |
| Journal website http://www.journalmc.org |
Case Report
Volume 8, Number 10, October 2017, pages 297-300
Spinal Instead of General Anesthesia for Two Pediatric Patients at Risk for Malignant Hyperthermia
Table
| Author | Demographic data | Outcomes |
|---|---|---|
| MH: malignant hyperthermia. | ||
| Mauritz et al [17] | Three adult, MH-susceptible patients. Epidural or spinal anesthesia. | Effective epidural or spinal anesthesia with no MH-related physiological changes. |
| Oikkonen et al [18] | Young adult male with prior history of MH during adolescence, presenting for thigh mass resection. | Respiratory distress after pre-medication with dantrolene, exaggerated by spinal block with 2 mL of hyperbaric lidocaine 5% at L3-4 with spread to the T3 dermatome. No other spinal anesthesia complications and no MH-related physiological changes. |
| Goto et al [19] | Adult female patient with prior history of MH, presenting for cesarean section. | Pretreatment with dantrolene prior to and after the procedure. Effective spinal anesthesia with no clinical signs or symptoms of MH. |
| Abballe [20] | MH susceptible woman, presenting for surgery for the removal of varicose veins. | Pretreatment with dantrolene prior to the procedure. Effective spinal anesthesia with no MH-related physiological changes. |
| Lucy [21] | Parturient with a family history of MH, presenting for a cesarean section. | Effective spinal anesthesia with hyperbaric bupivacaine 0.75% with 12.5 µg of fentanyl. Hypotension requiring ephedrine, but no other side effects of spinal anesthesia. No MH-related physiological changes. |
| Hsiao et al [22] | Patient with MELAS syndrome at risk for MH, presenting for an appendectomy. | Effective spinal anesthesia with no MH-related physiological changes. |
| Gupta and Purohit [23] | Adolescent female with osteogenesis imperfecta, considered at risk for MH, presenting for femoral nail removal. | Effective spinal anesthesia with 2.5 mL of hyperbaric bupivacaine (0.5%). No MH-related physiological changes. |