Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 11, Number 5, May 2020, pages 135-139

A Rare Case of Signet Cell Carcinoma of Transverse Colon in a Young Patient With Ulcerative Colitis


Figure 1.
Figure 1. (a) Low magnification view showing inflammatory change in ulcerative colitis, including crypt distortion, acute and chronic inflammation, and ulceration. (b) High-grade glandular dysplasia characterized by nuclear hyperchromasia, loss of nuclear polarity and increased mitotic activity.
Figure 2.
Figure 2. (a) Invasive nests of signet ring cell carcinoma arising from colonic mucosa. (b) Low magnification view showing signet ring cell carcinoma invading the muscularis propria of the colonic wall. (c) Lymphatic tumor invasion. (d) Mucicarmine stain highlighting cytoplasmic mucin of the metastatic signet ring cell carcinoma in a pericolic lymph node.