![Figure 1.](/tables/jmc375w-g001.jpg)
Figure 1. Non-contrasted CT thorax demonstrates large anterior mediastinal mass with associated bulky mediastinal and axillary lymphadenopathies, large right pleural effusion, and anasarca of upper chest wall and breasts.
![Figure 2.](/tables/jmc375w-g002.jpg)
Figure 2. Left axillary lymph node biopsy. (A) Poorly differentiated carcinoma with squamous features (hematoxylin-eosin stain, original magnification, x 400). (B) Tumor positive for cytokeratin (Immunostain for cytokeratin AE1/3, original magnification x 400). (C) Positive nuclear staining for P63 (Immunostain for P63, original magnification x 400) and (D) In-situ hybridization for Epstein-Barr virus shows strong positivity on tumor cells (EBER, original magnification x 400).
![Figure 3.](/tables/jmc375w-g003.jpg)
Figure 3. Anterior mediastinal mass biopsy. (A) Poorly differentiated carcinoma with squamous features (hematoxylin-eosin stain, original magnification, x 400). (B) Tumor positive for cytokeratin (Immunostain for pan-cytokeratin, original magnification x 400). (C) Positive nuclear staining for P63 (Immunostain for P63, original magnification x 400) and (D) In-situ hybridization for Epstein-Barr virus shows strong positivity on tumor cells (EBER, original magnification x 400).