Figure 1. (a-f) Computed tomography scan of chest, abdomen, and pelvis showing an extensive lymphadenopathy in the bilateral axillary region and in the mediastinum (yellow arrows) with bilateral pleural effusion noted (blue arrows). (a) Extensive lymphadenopathy in bilateral axillary region and in the mediastinum (yellow arrows). (b) Extensive lymphadenopathy involving the bilateral thoracic region and mediastinum (yellow arrows). (c) Extensive paraaortic and pre-vertebral lymphadenopathy (yellow arrows). (d) Extensive paraaortic wall lymphadenopathy (yellow arrows). (e) Extensive pelvic wall lymphadenopathy. (f) Discrete mass surrounding the rectum suspicious for malignancy.
Figure 2. (a, b) Hematoxylin and eosin (H&E) stain showing colonic mucosa with atypical proliferation of atypical lymphocytes, consistent with angioimmunoblastic T-cell lymphoma (AITL).
Figure 3. (a-c) Showing portions of lymphoid tissue with effacement of normal architecture by largely diffuse, polymorphic infiltrates of small- to medium-sized lymphocytes (frequently grouped showing clear cytoplasm), scattered large, transformed cells, many eosinophils and plasma cells. Background prominent vasculature, composed of arborizing high endothelial venules is evident. Large, atypical lymphocytes are positive for ICOS and CXCL-13 (d, e). ICOS: inducible T-cell co-stimulator; CXCL-13: chemokine (CXC motif) ligand 13.