Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 13, Number 8, August 2022, pages 374-379

Anti-MDA5 Associated Clinically Amyopathic Dermatomyositis With Rapidly Progressive Interstitial Lung Disease

Figures

Figure 1.
Figure 1. Posteroanterior (a) and lateral (b) chest X-ray demonstrating patchy atelectatic changes at bilateral lung bases (blue arrow).
Figure 2.
Figure 2. Computed tomography pulmonary angiogram (CTPA) of the chest in lung window demonstrating septal thickening (yellow arrows) and nonspecific patchy areas of atelectasis and increased interstitial markings at bilateral lung bases (green arrows).
Figure 3.
Figure 3. High resolution CT scan of the chest demonstrating traction bronchiectasis (red arrow), bilateral mixed interstitial and alveolar infiltrates (blue arrows), ground glass opacities (green arrows), and septal thickening (yellow arrows). CT: computed tomography.

Table

Table 1. Initial Laboratory Results
 
SerumResultsReference range
White blood cells (× 103/µL)7.54.5 - 11.0
Hemoglobin (g/dL)13.412.0 - 16.0
Mean corpuscular volume (fL)82.980.0 - 100.0
Platelet count (× 103/µL)364140 - 450
Glucose (mg/dL)96136 - 145
Blood urea nitrogen (mg/dL)105 - 25
Creatinine (mg/dL)0.740.44 - 1.0
Sodium (mmol/L)134135 - 146
Potassium (mmol/L)4.13.5 - 5.2
Chloride (mmol/L)9996 - 110
Bicarbonate (mmol/L)2424 - 31
Alkaline phosphatase (U/L)6338 - 126
Total protein (g/L)6.56.0 - 8.0
Albumin (g/dL)2.83.5 - 5
Bilirubin, total (mg/dL)0.90.2 - 1.3
Aspartate aminotransferase (U/L)8610 - 42
Alanine aminotransferase (U/L)6510 - 60
D-dimer (ng/mL)1,702≤ 500
C-reactive protein (mg/dL)3.700.00 - 0.74
Erythrocyte sedimentation rate (mm/h)520 - 20
Creatine kinase (IU/L)20020 - 232
Procalcitonin (ng/mL)0.07< 0.50
Blood culturesNegativeNegative
Sputum culturesNegativeNegative
Respiratory pathogen panelNegativeNegative