J Med Cases

Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc

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Case Report

Volume 14, Number 2, February 2023, pages 59-63

Chronic Oral Amiodarone as a Cause of Acute Liver Failure

Figure

Figure 1. Liver function test (LFT) trending before and after admission. AST: aspartate aminotransferase; ALT: alanine aminotransferase.

Tables

**Table 1.** Liver Function Test Trend Before Acute Presentation
	09/28/19	07/29/20	03/18/21	08/11/21	03/18/22	04/08/22	05/10/22
AST: aspartate aminotransferase; ALT: alanine aminotransferase.
ALT (U/L)	17	14	140	27	102	102	79
AST (U/L)	18	14	98	22	60	65	54
Alkaline phosphatase (U/L)	55	46	52	54	45	46	55
Total bilirubin (mg/dL)	0.9	1.0	1.3	0.9	1.0	0.8	0.9
Total protein (mg/dL)	5.9	5.8	6.0	6.4	6.2	6.1
Albumin (mg/dL)		3.7	3.8	3.7	3.4	3.5

**Table 2.** Laboratory ED Results, First Day
ED: emergency department; WBC: white blood cell; AST: aspartate aminotransferase; ALT: alanine aminotransferase.
WBC (× 10³/µL)	11.9
Hemoglobin (g/dL)	16.2
Platelets (× 10³/µL)	165
Sodium (mmol/L)	142
Creatinine (mg/dL)	0.99
Glucose (mg/dL)	112
Total protein (g/dL)	7.5
Serum albumin (g/dL)	4.4
Total bilirubin (mg/dL)	1.9
Bilirubin, direct (mg/dL)	0.2
AST (U/L)	87
ALT (U/L)	82
Alkaline phosphatase (U/L)	60

**Table 3.** Laboratory Results, Second Admission
	Day 1	Day 2	Day 3	Day 4	Day 5	Day 6
AST: aspartate aminotransferase; ALT: alanine aminotransferase; PT: prothrombin time; INR: international normalized ratio.
Total protein (g/dL)	6.5	5.5	5.2	4.4	4.9	4.9
Serum albumin (g/dL)	3.8	3.2	3	2.5	2.5	2.4
Total bilirubin (mg/dL)	1.6	1.6	2	2.4	2.2	1.6
Bilirubin, direct (mg/dL)	0.2	0.6	0.9	1.1	1.2	0.8
AST (U/L)	1,401	1,212	936	596	503	302
ALT (U/L)	1,589	1,400	1,138	725	637	458
Alkaline phosphatase (U/L)	49	44	44	43	55	56
PT (s)		30.2	18.5		12.1	11.4
INR		2.7	1.6		1.1	1