Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 14, Number 3, March 2023, pages 100-104

Metastatic Squamous Cell Carcinoma From Primary Hypopharynx Source to Gastric Mucosa Presenting as Massive Gastrointestinal Bleeding


Figure 1.
Figure 1. (a) The proximal end of PEG. (b) EGD showing an ulcerating circumferential gastric mass at the gastric body. PEG: percutaneous endoscopic gastrostomy; EGD: esophagogastroduodenoscopy.
Figure 2.
Figure 2. (a) H&E staining (× 100) of the biopsied gastric mass showing an invasive SCC (horizontal arrow) that concurred with the patient’s known hypopharyngeal SCC. (b) H&E (× 200) of the gastric biopsy with metastatic SCC (vertical arrow). (c) Immunohistochemistry staining (× 200) with strongly positive p63 uptake by the neoplastic cells (vertical arrow) confirming their SCC origin. H&E: hematoxylin and eosin; SCC: squamous cell carcinoma.
Figure 3.
Figure 3. Contrast-based CT scan of the abdomen with a gastric mass in the greater curvature (horizontal arrow). CT: computed tomography.