Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 14, Number 7, July 2023, pages 227-231


Intravenous Immunoglobulin-Associated Severe Hemolytic Anemia

Figures

Figure 1.
Figure 1. The peripheral smear demonstrating normocytic normochromic anemia with 3+ spherocytes. The arrowhead demonstrates the spherocytes.
Figure 2.
Figure 2. The bone marrow aspirate reveals erythroid hyperplasia. The arrowhead demonstrates the erythroid precursor cells with round dark nuclei without much cytoplasm.

Table

Table 1. Trend of Hemoglobin and Hemolysis Markers During Hospitalization and Follow-Up
 
Hemolysis markersDay 1 (day of presentation)Day 2Day 4 (day of discharge)Day 14 (follow-up 10 days after discharge)Reference range
Hemoglobin level (g/dL)8.38.510.312.913.5 - 17
Reticulocyte count (%)1313.6135.20.5-1.5%
Haptoglobin (mg/dL)< 30< 309718844 - 215
Lactate dehydrogenase (U/L)322308251174140 - 271
Total bilirubin (mg/dL)3.52.01.20.90.1 - 1.2