Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 15, Number 1, January 2024, pages 31-36

Early Detection and Diagnostic Approach Through Automated Hematological Analysis for Plasma Cell Leukemia

Figures

Figure 1.
Figure 1. Cytogram in ADVIA 2120: Baso channel (a) and Perox channel (b). An increase in cell count is observed in the Baso channel within the blast region (highlighted in white). The Perox channel reveals an elevation of cells identified as large unstained cells (highlighted in cyan).
Figure 2.
Figure 2. (a) Histogram of nucleated red blood cells in ADVIA 2021. A third peak is observed in orange (indicated by a white arrow), identifying non-stained cells with myeloperoxidase, which runs parallel to the lymphocyte peak in blue. (b) Plasma cell in peripheral blood film.
Figure 3.
Figure 3. Example of a normal hematological count in ADVIA 2021. (a) Perox channel: E = eosinophils, N = neutrophils, M = monocytes, L = lymphocytes, LUCs = large unstained cells. (b) Baso channel: B = basophils, PMN = polymorphonuclear cells, MN: mononuclear cells, Blast = blasts. (c) The nucleated red blood cell enumeration histogram corresponds to the unstained area on the Y-axis of the Peroxidase channel. This visualization depicts overlaps of non-stained cells (orange), platelets (white), nucleated red blood cells if present (yellow and red), and lymphocytes (blue).