J Med Cases

Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc

Journal website http://www.journalmc.org

Case Report

Volume 3, Number 1, February 2012, pages 63-67

A Rare Case of Collision Tumor: Coexistence of Adrenocortical Adenoma and Pheochromocytoma in the Same Adrenal Gland

Figures

Figure 1. A: Macroscopic appearance of the “adrenal mass” specimen composed of three pieces with a total weight of 36 grams. B: The cut surfaces of the nodules.

Figure 2. Histopathological features of pheochromocytoma of the adrenal gland in our patient. A: The trabecular architecture. B: The neoplastic cells diffusely stained with chromogranin. C: Immunoreactivity to S-100 in sustentacular cells. D: The neoplastic cells were negative for inhibin.

Figure 3. Histopathological features of adrenocortical adenoma of the adrenal gland in our patient. A: The neoplastic cells with intracytoplasmic lipid droplets or eosinophilic cytoplasm. B: The neoplastic cells were diffusely positive for inhibin.

Table

**Table 1.** Review of the English Literature for Adrenocortical Adenoma and Pheochromocytoma in the Same Adrenal Gland
Case	Age	Gender	Year*	Clinical presentation	Urine catecholamine	Reference
*The publication year of the reference; M: Male; F: Female; N/R: Not reported.
1	55	M	1952	Headache, hypertension	N/R	1
2	56	F	1977	Hypertension	Elevated	2
3	46	M	1985	Hypertension	Elevated	3
4	60	F	1986	Headache, hypertension, palpitation	Elevated	4
5	53	M	1988	Fatigue, weight loss	Elevated	5
6	59	F	2002	Silent	Normal	6
7	43	M	2006	Headache, hypertension, palpitation	Elevated	7
8	56	M	2006	Hypertension, chest pain	Elevated	7
9	51	F	2007	Hypertension	Elevated	8
10	40	F	2009	Hypertension	N/R	9
11	38	F	2011	Palpitation, chest pain	Elevated	Current