Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 3, Number 4, August 2012, pages 254-256

Malignant Transformation in a Typical Epidermal Cutaneous Cyst


Figure 1.
Figure 1. A typical epidermal cyst exhibiting granular cell layer and keratinisation (a and b: arrows). Malignant transformation into an acantholytic squamous cell carcinoma, without any dysplastic changes of the epithelium of the epidermal cyst (a and b: arrowheads) (Haematoxylin and eosin stained sections, x 100). Tumour cells showing nuclear polymorphism with hyperchromatism and keratinisation, loss of cellular cohesion and frequent mitoses (c and d: arrows) (Haematoxylin and eosin stained sections, c: x 200 and d: x 400).