Obstructive Uropathy by an Extraosseous Multiple Myeloma: A Case Report

Abstract

Multiple myeloma, characterized by plasma cell proliferation in the bone marrow, is the second most common hematologic malignancy. According to the 2003 Criteria for the Classification Monoclonal Gammapathies, Multiple Myeloma and Related Disorders, a clonal proliferation of plasma cells that occurs outside the bone marrow is referred to a plasmocytoma. Infrequently, patients with multiple myeloma are discovered to have an extramedullary plasma cell proliferation which cannot be categorized in the subgroups established by the International Myeloma Working Group. This clinical situation has been coined extraosseous multiple myeloma in recent medical literature. The following report is that of an extraosseous multiple myeloma causing an obstructive uropathy and acute renal failure. A brief literature review in relation to the case will complement the analysis of this rare finding.




J Med Cases. 2013;4(7):477-480
doi: http://dx.doi.org/10.4021/jmc1257w