Septic Cerebral Vein Thrombosis and Abnormal Leptomeningitis as a Complication From a Periodontitis in a Hispanic Male: Case Report and Literature Review

Sarmad Said, Chad J. Cooper, Haider Alkhateeb, Sucheta Gosavi, Ogechika Alozie


Sinus vein thrombosis is a rare form of stroke that results from thrombosis of the dural vein sinus. Despite the variety of diagnostic procedures and treatment, septic thrombosis of the cavernous sinus can cause significant morbidity and mortality if not diagnosed and treated as an emergency. The clinical presentation of proptosis that occurs suddenly accompanied by erythema of the eyelid and limitation of ocular movement should alert the clinician of the possibility of cavernous sinus thrombosis. A 38-year old Hispanic male presented with pounding headache, mainly in the occipital region that began 1 week prior to hospital admission. During the hospitalization the patient subsequently developed a progressive worsening of proptosis, lacrimation and neck pain. The MRI and venography of the brain showed a cerebral venous thrombosis (CVT) with a reactive diffuse leptomeningitis. The underlying cause was a chronic dental infection. The patient was treated with course of antibiotics and discharged. A few weeks later the repeated imaging studies showed a resolution of the CVT and leptomeningitis. Although rare, septic vein thrombosis (SVT) remains a potentially lethal complication of infections that involve the sinuses, face, ears and oral cavity. The early recognition and differentiation from other diseases are keys to reducing mortality rates and long-term sequelae. Advances in imaging, especially CT and MRI have contributed substantially to the rapid diagnosis of the condition.

J Med Cases. 2013;4(9):598-601


Periodontitis; Leptomeningitis; Cerebral vein thrombosis

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.