Oculobulbar Myasthenia Gravis in an Octogenarian

Olayinka A. Ogundipe, Alka Joshi, Helen E. Jones


This case describes an 89-year-old lady presenting with ‘slow progress with rehabilitation’ following the surgical repair of an osteoporotic hip fracture. She was noted to have symptoms and signs of insidious onset and of a progressive nature that were subsequently attributed to oculobulbar myasthenia gravis. The patient was seropositive for the acetylcholine receptor (AChR) antibody and also had features consistent with myasthenia gravis on a single fibre electromyography. She showed good clinical response to oral pyridostigmine and subsequently completed her rehabilitation and discharge planning uneventfully. A discussion on the basic epidemiology, clinical presentation, evaluation and treatment options for myasthenia gravis is presented.

J Med Cases. 2013;4(7):433-438
doi: https://doi.org/10.4021/jmc1281e


Acetylcholine receptors; Antibody; Frail elderly; Myasthenia gravis; Neuromuscular junction; Pyridostigmine bromide; Rehabilitation

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