Multiple Arthralgia After Use of Amoxicillin in EBV Infection: Could it be Adult Onset of Stills Disease?

Abstract

This case discusses about a rare development of adult-onset of stills disease in a 39-year-old male patient after taking amoxicillin for 14 days in an upper respiratory infection setting. It was confirmed later that he was in fact suffering from EBV infection at that time. Adult Onset Stills Disease (AOSD) is a rheumatic disease that tends to affect young adults between the ages of 16 and 35. This article presents an uncommon case of AOSD after use of amoxillcin with EBV infection. Stills disease is thought to be triggered by external infectious agents in genetically predisposed hosts, with many clinical manifestations of AOSD similar to those of self-limited viral infections. Major clinical manifestations include transient fever, rash, arthralgia and arthiritis, myalgia and liver abnormalities. Diagnosis of AOSD is typically based on clinical observation. Treatment for AOSD is empirical and centers on the use of NSAIDs, steroids and disease modifying anti-rheumatic drugs.




J Med Cases. 2014;5(2):105-107
doi: https://doi.org/10.14740/jmc1661w