Thiamine Deficiency (Beriberi) Induced Polyneuropathy and Cardiomyopathy: Case Report and Review of the Literature

Charles Qiming Cui, Ling L. Qiu


Thiamine, also known as vitamin B1, is an essential nutrient required for all living tissues. It can be found in high concentration inside the heart, kidneys, brain and skeletal muscles. A severe depletion is not commonly seen, except in cases of inadequate nutrition and/or alcoholism. The major manifestation of thiamine deficiency involves the nervous (dry beriberi, or neuropathy and/or Wernicke-Korsakoff syndrome) and cardiovascular (wet beriberi or cardiomyopathy) systems. This report details the case of a female patient with severe thiamine deficiency secondary to dysphagia caused by radiation injury. She developed debilitating polyneuropathy and cardiomyopathy with decreased ejection fraction. Early recognition and adequate thiamine replacement led to a full recovery in this case. In addition, we will discuss the potential benefits of thiamine supplementation in treating congestive heart failure.

J Med Cases. 2014;5(5):308-311


Thiamine; Beriberi; Heart failure

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.