Subfulminant Acute Liver Failure by Albendazole: Case Report

Jose Fabio Freire, Lopasso Maria Carolina, Lopes Gabriel Lima, Pereira Renner Augusto Raposo

Abstract


Acute hepatic failure is a rare and dramatic condition of acute loss of hepatocellular function, generally caused by virus, auto-immunity or drugs, either by idiosyncratic reaction or by dose-dependent injury. We present a case of hepatic injury induced by albendazole, an imidazole derivate, in a patient of 21 years old, who developed acute hepatic failure. She was included at the transplantation list, but had a great clinical evolution, with full recovery of the liver function only with support measures, prescinding of that treatment. In spite of this drug class presents with hepatotoxicity is already widely known fact, there are just few cases in the literature in association with hepatic failure.




J Med Cases. 2015;6(8):342-345
doi: http://dx.doi.org/10.14740/jmc2147w

Keywords


Hepatotoxicity; Albendazole; Acute liver failure

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