Concomitant Use of Cyclobenzaprine and Psychotropic Medications

Nevio Cimolai


Cyclobenzaprine has been cited as a co-factor or cause in serotonin syndrome following co-ingestion of other psychotropic medications. An observational study was conducted for a cumulative consumption of this agent among patients for 24 years, 8 months; no evidence of serotonin syndrome or malignant neuroleptic disorder was apparent despite a variety of concomitant psychotropic medications used.

J Med Cases. 2011;2(4):172-173


Cyclobenzaprine; Serotonin; Serotonin syndrome; Tricyclic; Toxicity

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