Molar Pregnancy and Poor Obstetrics Outcome: Retrospective Evaluation of Six Cases

Abstract

In this case series, we aimed to determine obstetrical history features of our patients who had experienced hydatidiform mole in their previous pregnancies. There were two patients who had heterozygous mutation for methylene tetrahydrofolate reductase (MTHFR) enzyme. One patient had both factor V Leiden and methylene tetrahydrofolate reductase enzyme heterozygous mutation. Excluding hydatidiform mole pregnancies, these six patients had 17 pregnancies totally. Eleven pregnancies (64.7%) experienced obstetrical/perinatal complications during their pregnancies. The most common complications were miscarriage, anomalous fetus, and mental retarded child. In conclusion, we advise obstetricians to be careful when their patients experienced hydatidiform mole in their previous pregnancies.




J Med Cases. 2016;7(6):239-241
doi: http://dx.doi.org/10.14740/jmc2495w