A Rare Case of Primary Angiosarcoma of Ovary in a Postmenopausal Woman

Kazila Bhutia, Jun Jie Wang, Shahul Hameed Mohamed Siraj, Wai Kheong Ryan Lee, May Ying Leong, Yong Kuei Lim


Primary angiosarcoma of the ovary is a rare and aggressive subset accounting for less than 1% of ovarian malignancies. We present a rare case of primary angiosarcoma of the ovary in a 52-year-old healthy postmenopausal woman who presented with mild abdominal pain, distension and poor appetite of 1 week duration. On abdominal examination, right iliac fossa fullness with shifting dullness was noted. A CT of abdomen and pelvis revealed a right 10.5 cm complex solid cystic mass with ascites and peritoneal nodularity. Her CA125 was 560 U/mL. She subsequently underwent full surgical staging and optimal debulking surgery. Final histology confirmed angiosarcoma of ovary grade 3 FIGO stage IIA ovarian cancer. A repeat CT of abdomen and pelvis done 4 weeks later prior to starting chemotherapy showed large 6.5 6 cm pelvic peritoneal deposits with cystic septation and solid components. Her disease progressed despite palliative chemotherapy and she unfortunately passed away several months after surgery. We reiterate that primary angiosarcoma of the ovary is an aggressive tumor with poor prognosis despite optimal surgical treatment.

J Med Cases. 2016;7(9):393-395
doi: https://doi.org/10.14740/jmc2606w


Angiosarcoma; Cancer; Ovary

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