Deplete and Delirious: A Report of Two Cases

Amanda Bryson, Melissa Yacur, Meeta Desai, Eileen Hennrikus


A diagnosis of thiamine deficiency and Wernickes encephalopathy should be considered in all elderly patients presenting to the emergency department with acute neurological changes. Physicians have an increased suspicion for the diagnosis in alcoholic patients, but unfortunately this condition is often missed in non-alcoholic patients. Timely diagnosis and treatment of these conditions is imperative due to the associated morbidity and mortality. In this report, we describe two cases of elderly patients who experience severe neurological disturbances secondary to Wernickes encephalopathy. Both patients conditions were worsened with an infusion of dextrose containing fluids and promptly improved with infusion of thiamine. We believe that acutely ill, elderly patients are particularly susceptible to thiamine deficiency and the development of Wernickes encephalopathy. The recognition of this population as especially vulnerable is critical in order to improve long-term neurological outcomes in these patients.

J Med Cases. 2017;8(4):108-110


Thiamine; Wernicke’s encephalopathy; Elderly

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.