Iron Overload Cardiomyopathy due to Non-Classical Hereditary Hemochromatosis

Ali Hamoudi, Vian Taqi


Hemochromatosis is defined as abnormal deposition of iron in body organs which can cause organ dysfunction. The most commonly affected organs are the liver, heart, endocrine glands, pancreas, joints and skin with manifestations of cirrhosis, cardiomyopathy, hypogonadism, endocrinopathies, diabetes mellitus, arthropathy, skin pigmentation, and increased risk of liver cancer in cirrhotic patients. The disease severity ranges from asymptomatic tissue damage with simple biochemical abnormalities detected incidentally to serious life-threatening disease that usually affects young people. Excessive iron accumulation in the body usually takes place either by genetic mutations causing increased gastrointestinal iron absorption (hemochromatosis) or secondary to excessive administration of exogenous iron by red blood cell transfusions or dietary sources (hemosiderosis). Cardiac hemochromatosis or primary iron-overload cardiomyopathy is recognized as the presence of systolic or diastolic cardiac dysfunction secondary to increased deposition of iron in the heart in the absence of other concomitant processes. Although heart failure secondary to iron overload could be lethal, it is potentially a preventable and a treatable disease when diagnosed and treated early in its course.

J Med Cases. 2019;10(2):58-61


Hemochromatosis; Phlebotomy; Cardiomyopathy; Atrial fibrillation

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.