Spontaneous Acute Mesenteric Thrombosis in a Patient With Hemoglobin E Thalassemia

Joseph Asemota, Ademola S. Ojo, Somtochukwu G. Ojukwu, Mohammed Saleh, Ravi Sarma


Acute mesenteric vein thrombosis (MVT) is an uncommon cause of mesenteric ischemia and portal hypertension. The common risk factors for the development of MVT include surgery, acute-intraabdominal inflammatory disorders, malignancies, and other prothrombotic states. However, MVT can occur in the absence of these risk factors. We describe the case of a 40-year-old man with a new diagnosis of hemoglobin E thalassemia and MVT and discuss the relationship between the hemoglobinopathy and thrombosis based on evidence from existing literature. The case emphasizes the importance of a high index of suspicion in the diagnosis of MVT in other to reduce complications and improve overall outcomes.

J Med Cases. 2022;13(8):421-426
doi: https://doi.org/10.14740/jmc3969


Mesenteric thrombosis; Mesenteric vein; Hemoglobinopathies; Hemoglobin E; Thalassemia

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