Cortical Blindness as an Unusual Adverse Drug Reaction

Abstract

Cortical blindness is a frightening and unusual adverse drug reaction that can be difficult to diagnose. It is characteristic of reversible posterior leukoencephalopathy syndrome (RPLS), which has been described as an idiosyncratic reaction to a variety of anti-cancer drugs. Here we describe a case of RPLS in a patient receiving treatment with an immunoconjugate, and review its association with anti-cancer drugs.




J Med Cases. 2010;1(2):47-50
doi: https://doi.org/10.4021/jmc47w