Inferior Vena Cava Filter Thrombosis in Protein-S Deficiency Patient due to Withdrawal of Anticoagulation Therapy After operation

Chang-Bae Sohn, Sea-Won Lee, Su-Hong Kim


In protein S deficiency, if there was recurrent thrombotic event, ongoing anti-coagulation therapy should be administered. Especially, in case of life threatening recurrent pulmonary embolism, prophylactic inferior vena cava (IVC) filter with anti-coagulation therapy may be considered. But until now, there is no definite guideline for anti-coagulation therapy duration about recurrent thrombotic events in protein S deficiency patients. A 64-year old male patient who already was diagnosed with protein S deficiency accompanied with recurrent pulmonary embolism and was performed IVC filter was referred to our hospital due to manage both leg edema after operation. In the abdominal CT, we could find IVC filter thrombosis occurred to withdrawal anti-coagulation therapy for 2 weeks after spine operation. So we performed catheter-based procedure with anti-coagulation therapy and successfully treated IVC filter thrombosis.

J Med Cases. 2013;4(9):612-615


Inferior vena cava; Filter thrombosis; Protein S deficiency; Pulmonary embolism

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