A Rare Syndrome in the Differential Diagnosis for Angioedema

Zeynep Celebi Sozener, Selcan Ozguclu, Omur Aydin, Aylin Okcu Heper, Sadan Soyyigit, Ayse Betul Sin


Melkersson-Rosenthal syndrome (MRS) is a rare, non-caseating chronic granulamatous neurocutaneous disease. MRS is frequently seen at the second or third decades of life. Classic triad was comprised of the recurrent facial nerve paralysis, orofacial edema and fissured dorsal tongue (lingua plicata). It is seen in 8-25% of the cases. The most important differential diagnosis of MRS is angioedema. Here we present two cases with MRS from our clinic. The first one is an example for the classic triad and the histopathological appearance is consistent with granulomatous cheilitis. The second case has an nonspesific histopathologic examination and was diagnosed clinically.

J Med Cases. 2014;5(11):579-582
doi: http://dx.doi.org/10.14740/jmc1543w


Angioedema; Melkersson-Rosenthal syndrome; Lingua plicata; Granulamatous cheilitis; Allergy

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.journalmc.org   editorial contact: editor@journalmc.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.