Angiosarcoma of the Thyroid Gland: A Case Report

Abstract

The authors described a case of rare histological type of primary thyroid tumor: angiosarcoma. We report a case of 37-year-old female who presented with the mass in the anterior of the neck that had been rapidly growing for several months. Scintigraphy showed a cold nodule in the left lobe of the thyroid. The patient underwent subtotal thyroidectomy. The cut surface showed a bulging solid grey hemorrhagic mass, measuring 6.5 cm at the lower pole of the left lobe. Microscopically a poorly differentiated highly desmoplastic polymorphocellular tumor. Immunohistochemically, the cells showed immunoreactivity for endothelial markers CD31, CD34, Facor VIII-related antigen and immunonegativity for epithelial markers including pancytokeratin, epithelial membrane antigen and thyroglobulin. Radiotherapy was applied. The patient was alive after a follow-up of 5 months.




J Med Cases. 2010;1(1):29-31
doi: https://doi.org/10.4021/jmc2010.07.107e