A 37-Year-Old Female With Abdominal Pain and Diarrhea: A Case of Idiopathic Hypereosinophilic Syndrome

Ivan E. Ramirez De Oleo, Abigail Lofchie, Mateo Mejia Saldarriaga, Muhammad Pervez


We report a case of a 37-year-old female who presented with diffuse abdominal pain associated with dysphagia, weight loss, and history of chronic non-bloody diarrhea. Labs showed severe eosinophilia and esophagogastroduodenoscopy (EGD) showed patchy erythema in antrum and body of the stomach. The pathological exam showed lymphoplasmacytic inflammation of lamina propria with increased eosinophil count and eosinophilic abscesses. The immunophenotypic analysis did not show evidence of clonality. There was no evidence of allergic reaction or infection. In view of the absence of causes to explain severe eosinophilia, the diagnosis of hypereosinophilic syndrome (HES) was made and she was started on steroids with improvement in her symptoms and eosinophils counts in subsequent evaluations.

J Med Cases. 2017;8(11):335-339
doi: https://doi.org/10.14740/jmc2813w


Hypereosinophilic syndrome; Eosinophilia; Strongyloides; FIP1L1-PDGFRA; Eosinophilic gastroenteritis; Bowel thickness

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