Isolated Optic Chiasmal Neuritis Secondary to Varicella-Zoster Virus Infection

Hiromasa Tsuda, Kozue Tanaka, Shuji Kishida, Noriko Ozaki


A 49-year-old woman without contributory medical history presented with zoster in the left-sided second cervical dermatome, and underwent oral valaciclovir at 3000 mg/day. Five days later, bitemporal hemianopia developed. Corrected visual acuities were spared, and funduscopic findings demonstrated no abnormalities in both eyes. Varicella-zoster virus (VZV) viremia was proved by the polymerase chain reaction test. Cerebrospinal fluid examination findings were normal. Cranial and orbital magnetic resonance imaging demonstrated no abnormalities. Thereafter, under 7 days of intravenous aciclovir at 1500 mg/day, bitemporal hemianopia gradually improved. This is a first reported case of isolated optic chiasmal neuritis secondary to VZV infection.

J Med Cases. 2011;2(6):289-291


Acyclovir; Bitemporal hemianopia; Chiasmitis (chiasmopathy); Optic chiasmal syndrome; VZV viremia

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