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Journal of Medical Cases

Case Report

Volume 14, Number 7, July 2023, pages 251-254

Efficacy and Safety of Carbon Dioxide Laser System in the Treatment of Scalp Sebaceous Adenoma With the Use of a New Scanner Unit

Sebaceous glands are distributed throughout the body, with the greatest number in the skin on the head and neck. They are a component on the pilosebaceous apparatus and are usually found in close association with hair follicles. The spectrum of sebaceous tumors ranges from the very common differentiated sebaceous hyperplasia to the rare and undifferentiated sebaceous carcinoma (SC) [1].

Sebaceous tumors can be grouped into three categories: sebaceous adenoma (SA), basal cell carcinoma with sebaceous differentiation, and SC [2]. Among these, SA is a rare solitary tumor that preferentially affects the forehead and scalp.

Although several treatment modalities have been reported, the full range and efficacy of options are unclear. Medications include antiandrogens, isotretinoin pills or capsules, trichloroacetic acid (rubbed onto your skin), cauterization, cryotherapy, excision, laser treatment, photodynamic therapy, and curettage [3].

Among these treatment therapeutic options, carbon dioxide (CO₂) laser has demonstrated its efficacy in the SA removal with excellent results [4]. As demonstrated in a recent study [5], CO₂ laser can produce considerable positive cosmetic outcomes with marked clinical improvement without any recurrence for SA removal and has been described to produce good (75%) clinical improvement and lesion shrinkage ranging from 50% to greater than 75% without lasting adverse effects.

In addition, it was also demonstrated from literature [6] that 8,040 SA lesions were successfully treated with CO₂ laser. The lesions were treated with freehand handpieces in which the laser beam is fixed; and it is the physician who has to move over the lesion in order to remove it completely, and for large lesions, this procedure could be lengthy.

For these reasons, the objective of this case report was to determine the efficacy and safety of a 10,600-nm CO₂ laser device in the treatment of large scalp SA, using a new scanning system which allows to speed up the removal of the lesion.

A 65-year-old male with a Fitzpatrick skin grade of III, was diagnosed with SA on the scalp area. The physical examination showed a 4 × 2 cm sized mass palpable in the center of patient’s scalp. Clinically, it occurs in the form of small skin reliefs (papules) appeared probably as a result of excessive sun exposure of the scalp area where the patient’s hair was thinner. Following the proper physical examination, a collection of patient’s anamnestic information to exclude familiarity with other more serious pathologies was done.

For the treatment of SA, patient underwent one session with the CO₂ laser system (DEKA MELA, Calenzano, Italy).

For this procedure, a new scanner system (DermaSCAN scanner, DEKA MELA, Calenzano, Italy) with 7-inch or 4-inch focal handpieces was used. During the initial phase, the 4-inch focal handpiece was used, and the following parameters were chosen to remove most of the lesion in a short time: power 4 - 10 W, dwell time 0.2 ms, a high-power pulse (UP/HP pulse) and cue ball for the scanning shape. In the final stages, however, the following parameters were used to refine the lesion: power 0.5 - 1 W, a high-power pulse (UP/HP pulse) and point (no scanning movement) for the shape. Finally, in order to give homogeneity and uniformity to the tissue, the following parameters were used with the 7-inch focal handpiece: power 8 - 15 W, dwell time 0.2 - 0.3 ms, CW pulse and hexagon for the shape.

This new scanning system is a microscanner that was developed for surgical dermatology treatments to enhance vaporization capability of standard freehand handpieces, and it is therefore particularly useful for those dermatological surgery treatments where larger areas need to be removed.

A local anesthesia with lidocaine was performed before laser treatment.

After treatment, it was suggested the application of topical antibiotics on the lesion covered by a hydrocolloid transparent patch. This patch has a high absorbency and can manage the exudate and secretions of the skin. The patient can remove the patch every day and wash the treated area with a cleansing foam and then reapply it, for 1 - 2 weeks, without crust formation, and protect the wound with sunscreen.

Some possible side effects such as dyschromia, burning sensation, bleeding and mild to moderate post-treatment erythema, itching, crusting, and edema, were checked.

In order to monitor the effectiveness of the treatment, clinical photos that documented the patient lesion were captured before treatment and at 1 month of follow-up. The patient’s informed consent was acquired regarding the risks, advantages, and treatment options.

The clinical and aesthetic results observed after laser procedure were excellent, as reported in Figure 1, with a complete remission of patient’s scalp SA lesion at 4 weeks’ follow-up. Patient satisfaction was very high, and no side effects were observed.

Click for large image

Figure 1. Case presentation of a 65-year-old male patient affected by sebaceous adenoma on the scalp area. (a) Before treatment. (b) A complete removal of lesion was observed at 4 weeks’ follow-up after the laser treatment session.

The CO₂ laser has been used extensively in dermatological surgery departments and is currently recognized as the gold standard for the vaporization of soft tissues [7, 8].

The CO₂ laser therapy is common successfully used for cutaneous disorder associated with cosmetic problems, such as sebaceous gland hyperplasia [9] nevus sebaceous [10] eccrine hidrocystomas [11], and common dermatosis like the severe Favre-Racouchot syndrome [12]. Recent studies also demonstrated the efficacy of this system in the management of burn and postsurgical scars [13, 14].

Furthermore, the CO₂ laser can be used in any phototype and race, provides a safe and effective result for different dermatological pathologies [15].

The advantages of CO₂ laser include a reduced healing time, an infrequent need for anesthesia, reduced thermal damage, less bleeding, less inflammation, and minimal undesirable side effects (unaesthetic scarring and dyschromic effects). These benefits must be considered in comparison with other available surgical techniques such as diathermo-coagulation and traditional surgery, which on the contrary necessitate frequent anesthetics, a longer recovery period, a slower cicatrization, and a high incidence of hypertrophic scars and keloids. Another relevant limitation of these two surgical treatments is its limited usage in many anatomically difficult areas such as the internal corner of the eyes, the ears, the alae of the nose, and the genital areas characterized by a high incidence of cutaneous damage upon using these techniques. The laser CO₂ technique is preferred in patients with several or wide lesions, those with a pacemaker, or for patients who cannot be subjected to anesthetics [16-19].

The greater advantage of DermaSCAN is represented by its ability to speed up the ablation/vaporization procedures thanks to the specific emission modes designed for this scanner. This scanner allows to reach both a deep ablation in the tissue (first ablation phase) alternating with a more superficial and gentle vaporization (second ablation phase), which give a final definition of the skin lesion. In fact, the selection of the cue ball scan figure is indicated to perform a fast ablation generally in the initial stages of dermatological procedures when it is necessary to remove larges volumes. The selection of the point scan shape (no scanning movement, the scanner is operative but fixed on one point), instead, allow you to use the freehand handpiece without having to remove the scanner and therefore have a more superficial ablation to better definition of the lesion. Finally, the use of hexagon shape allows homogenization and uniformity of the tissue. This laser system technology actually allows for precise, effective, and targeted action on the lesions treated while simultaneously protecting the surrounding areas, ensuring the best possible re-epithelialization. As a result, it is appropriate for surgical procedures because the reduced inflammatory response promotes faster healing. Due to the application’s extreme accuracy, it is possible to vaporize the epidermis horizontally on its own or to extend the thermal effect even further into the papillary or reticular derma with a control of tissue damage and spare vertically the hair follicles while simultaneously maximizing efficacy.

Indeed, our results demonstrated the effectiveness of the treatment, with clinical photos that documented the complete remission of patient’s scalp SA lesion at 4 weeks’ follow-up. Patient satisfaction was very high, and no side effects were observed.

Our future goal will be to increase the clinical cases involving more patients to reconfirm the effectiveness of treatment.

The purpose of the present investigation was to assess the efficacy and safety of a 10,600-nm CO₂ laser device in the treatment of large scalp SA using a new scanning system (DermaSCAN) that allows for faster lesion removal. The clinical and aesthetic results observed after laser procedure were excellent, with a complete remission of patient’s scalp SA lesion at 4 weeks’ follow-up. Patient satisfaction was very high, and no side effects were observed. Our future goal will be to increase the clinical cases involving more patients to reconfirm the effectiveness of treatment.

Acknowledgments

None to declare.

Financial Disclosure

No funding was provided for this study.

Conflict of Interest

Authors IF, TZ, FM, GG were employed by El.En. Group. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationship that could be construed as a potential conflict of interest.

Informed Consent

Informed consent was obtained.

Author Contributions

Conceptualization, methodology, software, investigation, project administration, and funding acquisition: PB, GG and TZ. Resources: PB, GG, FM and TZ. Writing-original draft preparation: IF and FM. Validation, formal analysis, data curation, writing-review and editing, visualization, and supervision: PB, GG, IF, FM and TZ. All authors have read and agreed to the published version of the manuscript.

Data Availability

The data supporting the findings of this study are available from the corresponding author upon reasonable request.

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Journal of Medical Cases is published by Elmer Press Inc.