A 65-year-old Female With a Rapidly Growing Painless Occipital Mass Encircling the Foramen Magnum

Harry Haynes, Dan Taylor, Nicki Cohen


Solitary plasmacytoma of bone is a rare disorder accounting for 5-10% of plasma cell dyscrasias with most patients progressing to myeloma. Here the authors present a case of a 65-year-old female who presented with a hard occipital lump. An MRI demonstrated extensive mass distortion of the right cerebellar hemisphere. This was biopsied showing a cluster of plasma cells with discohesive, monomorphic cells, cytoplasmic clearing or hoff, and characteristic clock-face nuclei. The patient had no symptoms other than neck pain, headaches and the hard occipital mass. Solitary plasmacytoma of bone is only diagnosed where there is no evidence to support myeloma as a diagnosis, and investigations are tailored towards this. Radiotherapy is the mainstay of treatment and patients should be monitored for the development of myeloma.

J Med Cases. 2013;4(2):83-85
doi: https://doi.org/10.4021/jmc934w


Plasmacytoma; Neurosurgery; Neuropathology

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.journalmc.org   editorial contact: editor@journalmc.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.